CVE-2026-31973
High · 7.5CVSS
7.5
EPSS
0.6%
Published
Mar 18, 2026
CISA due date
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The record
SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Affected packages
| Ecosystem | Package | Introduced | Fixed |
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